Hydrofluoric acid (HF) can burn through glass or concrete. Fluoride ions are absorbed through the skin, destroying tissue until they are sequestered in the bones. HF damage causes severe, long-term pain and slow-healing burns and can be deadly. Significant delays between exposure and symptom onset may occur.

Some possible complications of exposure
- Airway compromise and swelling in the respiratory tract
- Corneal perforation and blindness
- Pulmonary edema (fluid in the lungs)
- Arrhythmia (irregular heartbeat)
- Burns may involve underlying bone
- Tissue destruction
- Electrolyte abnormalities
- Scarring
- Loss of digits
- Penetrates fingernails and burns the pulp beneath without destroying nails. Treatment can require the removal of the nail